This medication may reduce your risk of getting HIV. Here’s what you need to know.
Because there is not yet a cure for HIV, or the human immunodeficiency virus, prevention efforts play a key role in managing the HIV/AIDS epidemic. Two major preventative measures for HIV include PrEP (pre-exposure prophylaxis) and PEP (post-exposure prophylaxis).
The difference between PrEP and PEP is somewhat similar to the difference between a standard birth control pill and emergency contraceptive pills (e.g., Plan B). Like a daily birth control pill to prevent pregnancy, PrEP is an oral pill that at-risk individuals take each day to prevent HIV infection. Learn more about what PrEP for HIV is here.
PEP, on the other hand, is an HIV prevention method that you can take after a high-risk exposure to the virus, according to hematologist Jeffrey Laurence, MD, of Weill Cornell Medicine and NewYork-Presbyterian Hospital. Similar to an emergency contraceptive, PEP for HIV must be started within 72 hours after exposure to the virus, whether from a broken condom, unprotected sex, rape, sharing needles, accidental contact with an infected needle, or other forms of contact.
After exposure to HIV, PEP uses antiretroviral medicines to block HIV from permanently infecting the body, says Dr. Laurence. PEP requires taking three pills a day for 28 days, and you will need to follow up with your doctor throughout the month to test for HIV and other complications, according to the U.S. Department of Health and Human Services.
If you believe you may have been exposed to HIV, you should call your doctor right away to begin preventive treatment.
However, if you have an ongoing risk of being exposed to HIV, your best option is taking PrEP (pre-exposure) instead of PEP (post-exposure). Find out more about who should take PrEP to prevent HIV.
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Post-exposure prophylaxis is, you've
done something you shouldn't have done.
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Something happened, the condom broke,
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you forgot to take your
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You're in a situation you couldn't
prevent it in terms of a rape,
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when you may not know the status
of the partner that raped you.
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And it can also be used, of course, if
you've had an accidental needle stick, or
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That okay, if something went wrong or
you drank too much and
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you woke up [LAUGH] in a place you didn't
wanna be, that we have something else.
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And that's called
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I feel that you need to take
it within 48 hours, but
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officially 72 hours we can start
you not on the one pill, one a day.
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You really do need three
medications to take for a month.
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And that is incredibly effective
at blocking your body from getting
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HIV after you've been exposed.
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And I've been associated with that over
the years, with many, many people.
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Because of condom breakage, because of
physicians sticking themselves with
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needles of someone who is not on
HIV medications, it's an emergency.
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All emergency rooms in America now
are equipped to handle this and
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help you not get that infection.
HIV/AIDS: PEP. Atlanta, GA: Centers for Disease Control and Prevention, 2017. (Accessed on August 21, 2017 at https://www.cdc.gov/hiv/basics/pep.html.)
HIV prevention: Post-exposure prophylaxis (PEP). Rockville, MD: U.S. Department of Health and Human Services, 2017. (Accessed on August 21, 2017 at https://aidsinfo.nih.gov/understanding-hiv-aids/fact-sheets/20/87/post-exposure-prophylaxis--pep-.)